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Found 2 Enz. Inhib. hit(s) with Target = 'Kelch-like ECH-associated protein 1' and Ligand = 'BDBM50190617'
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50190617(CHEMBL3827626)
Affinity DataIC50:  100nMAssay Description:Inhibition of human Keap1 kelch domain (Ala321 to Thr609 residues) binding to fluorescent labeled Nrf2 peptide preincubated for 15 mins followed by N...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50190617(CHEMBL3827626)
Affinity DataIC50:  140nMAssay Description:Inhibition of FITC-9mer Nrf2 peptide binding to recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed