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Report error Found 3 Enz. Inhib. hit(s) with Target = 'L-lactate dehydrogenase A chain' and Ligand = 'BDBM50250665'
TargetL-lactate dehydrogenase A chain(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250665(CHEMBL4076264 | US10961200, Compound 425 | US11247...)
Affinity DataIC50:  95nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and in absence of EDTA by diaphorase/resazurin ba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250665(CHEMBL4076264 | US10961200, Compound 425 | US11247...)
Affinity DataIC50: >5.70E+4nMAssay Description:Test compounds were placed in a Greiner Bio-One (Monroe, N.C.) 1536-well black solid bottom assay plate. 200 millimolar (mM) Tris HCl, pH 7.4, 100 mi...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetL-lactate dehydrogenase A chain(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50250665(CHEMBL4076264 | US10961200, Compound 425 | US11247...)
Affinity DataIC50: >5.70E+4nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and in absence of EDTA by diaphorase/resazurin ba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed