Report error Found 8 Enz. Inhib. hit(s) with Target = 'LIM domain kinase 2' and Ligand = 'BDBM50591082'
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant LIMK2 (347 to 659 residues) (unknown origin) incubated for 45 mins followed by ATP addition measured after 180 mins by Rapi...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of PAK mediated recombinant LIMK2 phosphorylation (347 to 659 residues) (unknown origin) incubated for 45 mins followed by ATP addition me...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant LIMK2 (330 to 632 residues) (unknown origin) expressed in baculovirus infected insect cells using CFL1 as substrate preincu...More data for this Ligand-Target Pair
Affinity DataIC50: 91nMAssay Description:Inhibition of recombinant full length LIMK2 (330 to 632 residues) (unknown origin) expressed in HEK293T cells incubated for 2 hrs in presence of trac...More data for this Ligand-Target Pair
Affinity DataIC50: 191nMAssay Description:Inhibition of recombinant LIMK2(unknown origin) expressed in HEK293 cells using NanoGlo substrate incubated for 2 hrs followed by substrate addition ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.32E+3nMAssay Description:Inhibition of LIMK2 in human HeLa cells lysate incubated for 45 mins by kinobead based pulldown assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.66E+3nMAssay Description:Binding affinity to LIMK2 in human HeLa cells assessed as apparent dissociation constant incubated for 45 mins by kinobead based pulldown assayMore data for this Ligand-Target Pair
Affinity DataKd: 64nMAssay Description:Binding affinity to human wild-type full length LIMK2 (M1 to P638 residues) expressed in bacterial expression system assessed as dissociation constan...More data for this Ligand-Target Pair