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Found 1 Enz. Inhib. hit(s) with Target = 'Leukotriene C4 synthase' and Ligand = 'BDBM223289'
TargetLeukotriene C4 synthase(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM223289((1S,2S)-2-({5-[(5-Chloro-2,4-difluorophenyl)(propy...)
Affinity DataIC50:  0.483nMpH: 7.5Assay Description:In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester. In order to obtain IC50-v...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent