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Found 2 Enz. Inhib. hit(s) with Target = 'Lys-gingipain W83' and Ligand = 'BDBM453312'
TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandPNGBDBM453312(BDBM453343 | BDBM553818 | US10730826, Compound 12a)
Affinity DataIC50:  0.0800nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandPNGBDBM453312(BDBM453343 | BDBM553818 | US10730826, Compound 12a)
Affinity DataIC50:  0.0800nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent