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Report error Found 2 Enz. Inhib. hit(s) with Target = 'Lysosomal acid glucosylceramidase' and Ligand = 'BDBM285845'
TargetLysosomal acid glucosylceramidase(Human)
Alectos Therapeutics

US Patent
LigandPNGBDBM285845((6R,7R,8S)-8-(4-fluorobut-1-yn-1-yl)-4-azaspiro[2....)
Affinity DataIC50:  2.5nMAssay Description:Various concentrations of test compounds were prepared in DMSO and then diluted into buffer consisting of 50 mM sodium phosphate 0.25% w/v sodium tau...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetLysosomal acid glucosylceramidase(Human)
Alectos Therapeutics

US Patent
LigandPNGBDBM285845((6R,7R,8S)-8-(4-fluorobut-1-yn-1-yl)-4-azaspiro[2....)
Affinity DataIC50:  2.5nMpH: 7.0Assay Description:Various concentrations of test compounds were prepared in DMSO and then diluted into buffer consisting of 50 mM sodium phosphate 0.25% w/v sodium tau...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent