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Found 2 Enz. Inhib. hit(s) with Target = 'MAP kinase-activated protein kinase 2' and Ligand = 'BDBM50297118'
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297118((R)-10-Methyl-3-o-tolyl-9,10,11,12-tetrahydro-7-th...)
Affinity DataIC50:  30nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297118((R)-10-Methyl-3-o-tolyl-9,10,11,12-tetrahydro-7-th...)
Affinity DataIC50:  3.36E+3nMAssay Description:Inhibition of MK2 in human U937 cells assessed as blockade of LPS-stimulated TNFalpha productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed