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Found 4 Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 3' and Ligand = 'BDBM50581319'
TargetMelanocortin receptor 3(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50581319(BIM-22493 | RM-493 | SETMELANOTIDE | Setmelanotide)
Affinity DataKi:  13nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC3R expressed in HEK2936E cell membrane measured after 16-23 hrs by 1450 microbeta trilux scintillat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50581319(BIM-22493 | RM-493 | SETMELANOTIDE | Setmelanotide)
Affinity DataKi:  13nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC3R expressed in HEK2936E cell membrane measured after 16 to 23 hrs by 1450 microbeta trilux scintil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50581319(BIM-22493 | RM-493 | SETMELANOTIDE | Setmelanotide)
Affinity DataEC50:  0.151nMAssay Description:Agonist activity at human MC3R expressed in HEK2936E cells assessed as cAMP production in presence of IBMX by time resolved fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50581319(BIM-22493 | RM-493 | SETMELANOTIDE | Setmelanotide)
Affinity DataEC50:  0.151nMAssay Description:Agonist activity at human melanocortin receptor 3 expressed in human T-REx-293 cells assessed as stimulation of intracellular cAMP accumulation incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed