Found 9 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 3' and Ligand = 'BDBM50121643' 
Affinity DataKi: 156nMAssay Description:Displacement of [3H]-459477 from human recombinant mGlu3 receptor expressed in AV12 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 2.73E+3nMAssay Description:Antagonist activity at human recombinant mGlu3 receptor expressed in AV12 cells assessed as reversal of DCG-4-inhibited, forskolin-stimulated cAMP pr...More data for this Ligand-Target Pair
Affinity DataIC50: 2.52E+4nMAssay Description:Antagonist activity at human recombinant mGlu3 receptor expressed in AV12 cells assessed as inhibition of glutamate-stimulated Ca2+ mobilization afte...More data for this Ligand-Target Pair
Affinity DataEC50: 1.18E+3nMAssay Description:Agonist activity at human recombinant mGlu3 receptor D279E and Q306L mutant expressed in AV12 cells assessed as stimulation of Ca2+ mobilization afte...More data for this Ligand-Target Pair
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at human recombinant mGlu3 receptor expressed in AV12 cells assessed as stimulation of Ca2+ mobilization after 1.5 hrs by FLIPR assa...More data for this Ligand-Target Pair
Affinity DataEC50: 2.18E+3nMAssay Description:Agonist activity at human recombinant mGlu3 receptor D279E mutant expressed in AV12 cells assessed as stimulation of Ca2+ mobilization after 1 hr by ...More data for this Ligand-Target Pair
Affinity DataEC50: 5.68E+3nMAssay Description:Agonist activity at wild type human recombinant mGlu3 receptor expressed in AV12 cells assessed as stimulation of Ca2+ mobilization after 1 hr by FLI...More data for this Ligand-Target Pair
Affinity DataEC50: 129nMAssay Description:Agonist activity at human recombinant mGlu3 receptor expressed in AV12 cells assessed as inhibition of forskolin-stimulated cAMP production after 1 h...More data for this Ligand-Target Pair
Affinity DataEC50: 2.83E+3nMAssay Description:Agonist activity at human recombinant mGlu3 receptor Q306L mutant expressed in AV12 cells assessed as stimulation of Ca2+ mobilization after 1 hr by ...More data for this Ligand-Target Pair
