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Report error Found 2 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM136048'
TargetMetabotropic glutamate receptor 5(Human)
Novartis

US Patent
LigandPNGBDBM136048(US8853203, 92 | US9650377, Example 92)
Affinity DataIC50: <1nMAssay Description:Activity of compounds of the present invention with respect to mGluR1 antagonism was examined by an assay based on measurements of L-glutamate induce...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetMetabotropic glutamate receptor 5(Human)
Novartis

US Patent
LigandPNGBDBM136048(US8853203, 92 | US9650377, Example 92)
Affinity DataIC50: <1nMAssay Description:Activity of compounds of the present invention was examined by determination to what extent the glutamate-induced elevation of the intracellular calc...More data for this Ligand-Target Pair
In DepthDetails US Patent