Found 2 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50177097'
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 500nMAssay Description:Displacement of [3H]MPEP from rat cortex mGluR5More data for this Ligand-Target Pair
Affinity DataIC50: 890nMAssay Description:Antagonist activity at human mGluR5 expressed in 1321N1 cells assessed as effect on L-glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair