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Report error Found 2 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50258331'
TargetMetabotropic glutamate receptor 5(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50258331(3-Cyano-4'-(3-fluorophenyl)-N-(6-methylpyridin-2-y...)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]MPEP from cloned mGluR5 (unknown origin) expressed in HEK293T cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50258331(3-Cyano-4'-(3-fluorophenyl)-N-(6-methylpyridin-2-y...)
Affinity DataIC50:  25nMAssay Description:Antagonist activity at rat mGluR5 expressed in HEK293A cells assessed as glutamate-induced calcium flux preincubated for 140 sec before glutamate cha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed