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Report error Found 2 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50334119'
TargetMetabotropic glutamate receptor 5(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334119((3-(3-phenylprop-1-ynyl)phenyl)(4-(pyridin-2-yl)pi...)
Affinity DataKi:  139nMAssay Description:Displacement of [3H]-MPEP from rat mGluR5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334119((3-(3-phenylprop-1-ynyl)phenyl)(4-(pyridin-2-yl)pi...)
Affinity DataIC50:  163nMAssay Description:Antagonist activity at rat mGluR5 expressed in HEK293 cells assessed as inhibition of L-glutamate-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed