Found 3 Enz. Inhib. hit(s) with Target = 'Microsomal triglyceride transfer protein large subunit' and Ligand = 'BDBM50204367' TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 0.0110nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of MTP assessed as inhibition of apoB secretion from human HepG2 cellsMore data for this Ligand-Target Pair
