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Report error Found 3 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50175761'
TargetMitogen-activated protein kinase 14(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50175761(7-(1-tert-butylpiperidin-4-yl)-5-(2-chloro-4-fluor...)
Affinity DataIC50:  0.380nMAssay Description:Inhibition of P38 alpha MAPKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50175761(7-(1-tert-butylpiperidin-4-yl)-5-(2-chloro-4-fluor...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of TNF alpha release in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50175761(7-(1-tert-butylpiperidin-4-yl)-5-(2-chloro-4-fluor...)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of LPS stimulated TNF alpha release in whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed