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Found 3 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase kinase 1' and Ligand = 'BDBM552516'
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Merck Sharp &Amp

WIPO
LigandPNGBDBM552516(WO2022098809, Example 4-3 | WO2022098809, Example ...)
Affinity DataIC50:  0.260nMAssay Description: Compounds are serially diluted (3-fold in 100% DMSO) across a 384-well polypropylene source plated from column 3 to column 12 and column 13 to colum...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Merck Sharp &Amp

WIPO
LigandPNGBDBM552516(WO2022098809, Example 4-3 | WO2022098809, Example ...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of HPK1 (unknown origin) using SLP76 as substrate incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Merck Sharp &Amp

WIPO
LigandPNGBDBM552516(WO2022098809, Example 4-3 | WO2022098809, Example ...)
Affinity DataIC50:  0.300nMAssay Description: Compounds are serially diluted (3-fold in 100% DMSO) across a 384-well polypropylene source plated from column 3 to column 12 and column 13 to colum...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed