Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 2 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase kinase 1' and Ligand = 'BDBM591249'
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM591249(2-((8-amino-6-(5-amino-4- methylpyridin-3-yl)-7-fl...)
Affinity DataKi:  0.0130nMAssay Description:Inhibition of full-length HPK1 (unknown origin) assessed as inhibition constant in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM591249(2-((8-amino-6-(5-amino-4- methylpyridin-3-yl)-7-fl...)
Affinity DataKi:  0.0130nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent