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Found 4 Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM50292912'
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkermes

Curated by ChEMBL
LigandPNGBDBM50292912(17-Cyclopropylmethyl-3,14beta-dihydroxy-4,5r-epoxy...)
Affinity DataKi:  0.00130nMAssay Description:Displacement of [3H]-DAMGO from human HA-tagged mu-opioid receptor expressed in HEK293 cells after 90 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkermes

Curated by ChEMBL
LigandPNGBDBM50292912(17-Cyclopropylmethyl-3,14beta-dihydroxy-4,5r-epoxy...)
Affinity DataKi:  56nMAssay Description:Activity at monocloned mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkermes

Curated by ChEMBL
LigandPNGBDBM50292912(17-Cyclopropylmethyl-3,14beta-dihydroxy-4,5r-epoxy...)
Affinity DataEC50:  0.300nMAssay Description:Agonist activity at human mu-opioid receptor expressed in HEK293 cell membranes after 1 hr by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkermes

Curated by ChEMBL
LigandPNGBDBM50292912(17-Cyclopropylmethyl-3,14beta-dihydroxy-4,5r-epoxy...)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human mu-opioid receptor expressed in HEK293 cells coexpressing delta6-Galphaqi4-myr assessed as induction of intracellular calci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed