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Found 3 Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M4' and Ligand = 'BDBM50268390'
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50268390(CHEMBL4071900)
Affinity DataKi:  7.80nMAssay Description:Displacement of [3H]NMS from human recombinant muscarinic M4 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50268390(CHEMBL4071900)
Affinity DataIC50:  110nMAssay Description:Antagonist activity at human recombinant muscarinic M4 receptor expressed in CHO cells co-transfected with Gqi5 in presence of EC80 acetylcholine by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50268390(CHEMBL4071900)
Affinity DataIC50:  120nMAssay Description:Antagonist activity at human recombinant muscarinic M4 receptor expressed in CHO cells co-transfected with Gqi5 in presence of EC80 acetylcholine by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed