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Report error Found 4 Enz. Inhib. hit(s) with Target = 'Neprilysin' and Ligand = 'BDBM50002022'
TargetNeprilysin(Rabbit)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50002022((2-Benzyl-3-hydroxycarbamoyl-propionylamino)-aceti...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of neutral endopeptidase activity in rabbit kidney with 20 nM [3H]-D-Ala2-Leu-enkephalin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50002022((2-Benzyl-3-hydroxycarbamoyl-propionylamino)-aceti...)
Affinity DataIC50:  1.40nMAssay Description:Inhibitory potency against neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50002022((2-Benzyl-3-hydroxycarbamoyl-propionylamino)-aceti...)
Affinity DataIC50:  1.40nMAssay Description:In vitro inhibition of enkephalinase purified from rat kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Rabbit)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50002022((2-Benzyl-3-hydroxycarbamoyl-propionylamino)-aceti...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of [3H]Ala2-Leu-enkephalin binding to Neutral endopeptidase (NEP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed