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Found 2 Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-3/beta-4' and Ligand = 'BDBM50270397'
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rattus norvegicus (Rat))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50270397(CHEMBL4070098)
Affinity DataKi:  1.10E+4nMAssay Description:Displacement of [3H]epibatidine from rat alpha3beta4 nAChR expressed in HEK293 cell membranes after 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rattus norvegicus (Rat))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50270397(CHEMBL4070098)
Affinity DataIC50:  5.00E+4nMAssay Description:Antagonist activity at rat alpha3beta4 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up to...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed