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Report error Found 4 Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-4/beta-2' and Ligand = 'BDBM50069846'
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50069846(3-Butyl-5-((S)-1-methyl-pyrrolidin-2-ylmethoxy)-py...)
Affinity DataKi:  0.160nMAssay Description:Stimulation of cation efflux in human nAChR alpha4-beta2 expressing K177 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50069846(3-Butyl-5-((S)-1-methyl-pyrrolidin-2-ylmethoxy)-py...)
Affinity DataIC50:  640nMAssay Description:Inhibitory concentration to antagonise cation efflux in nAChR subtype human alpha3betaX, expressed in IMR-32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50069846(3-Butyl-5-((S)-1-methyl-pyrrolidin-2-ylmethoxy)-py...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of cation efflux in human nAChR alpha4-beta2 expressing K177 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50069846(3-Butyl-5-((S)-1-methyl-pyrrolidin-2-ylmethoxy)-py...)
Affinity DataEC50: >1.00E+6nMAssay Description:Binding affinity towards nAChR (alpha4-beta2) by the displacement of [3H]-(-)-cytisine in whole rat brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed