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Found 5 Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-7' and Ligand = 'BDBM50399292'
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50399292(CHEMBL2180842)
Affinity DataKi:  390nMAssay Description:Displacement of [3H]-epibatidine from rat alpha7 nAchR expressed in rat GH4C1 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50399292(CHEMBL2180842)
Affinity DataEC50:  1.00E+4nMAssay Description:Agonist activity at human alpha7 nAchR by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50399292(CHEMBL2180842)
Affinity DataEC50:  740nMAssay Description:Agonist activity at rat alpha7 nAchR expressed in rat GH4C1 cells assessed as stimulation of calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50399292(CHEMBL2180842)
Affinity DataEC50:  1.07E+4nMAssay Description:Agonist activity at rat alpha7 nAchR expressed in rat GH4C1 cells by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50399292(CHEMBL2180842)
Affinity DataEC50:  741nMAssay Description:Agonist activity at rat alpha7 nAchR expressed in rat GH4C1 cells assessed as stimulation of calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed