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Report error Found 2 Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma' and Ligand = 'BDBM220218'
TargetNuclear receptor ROR-gamma(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM220218(US9290476, 61)
Affinity DataIC50:  6.60nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM220218(US9290476, 61)
Affinity DataKd:  5nMAssay Description:Displacement of 1,8-ANS from human N-terminal His-tagged RORgammat LBD (850 to 1635 residues) expressed in Escherichia coli by thermofluor assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed