Report error Found 4 Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma' and Ligand = 'BDBM392075'
Affinity DataIC50: 1.40nMAssay Description:Inverse agonist activity at human GAL4 DBD-fused RORgammat LBD (237 to 497 residues) expressed in HEK293T cells assessed as reduction in ROR mediated...More data for this Ligand-Target Pair
Affinity DataEC50: 68nMAssay Description:Inverse agonist activity at RORgammat in human whole blood assessed as reduction in IL17A productionMore data for this Ligand-Target Pair
Affinity DataEC50: 2.20nMAssay Description:Binding affinity to recombinant human RORgamma LBD (237 to 497 residues) expressed in Escherichia coli BL21 (DE3) GOLD by 1,8-ANS dye-based thermoflu...More data for this Ligand-Target Pair
Affinity DataKd: 0.110nMAssay Description:Binding affinity to recombinant human RORgamma LBD (237 to 497 residues) expressed in Escherichia coli BL21 (DE3) GOLD by 1,8-ANS dye-based thermoflu...More data for this Ligand-Target Pair