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Found 2 Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma [238-497]' and Ligand = 'BDBM175851'
TargetNuclear receptor ROR-gamma [238-497](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM175851(US9688684, Compound 48: 7-(3-Isopropyl-1-phenyl-1H...)
Affinity DataIC50:  500nMpH: 6.8Assay Description:In this assay, a GST-tagged human RORγ ligand binding domain (GST-hRORγ-LBD) interacts with a synthetic biotinylated TRAP220 cofactor pepti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma [238-497](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM175851(US9688684, Compound 48: 7-(3-Isopropyl-1-phenyl-1H...)
Affinity DataIC50:  2.50E+4nMAssay Description:For the assay 12,500 293T cells (DSMZ no ACC 635) per 384 well are seeded in 30 μl inMEM Eagle medium, supplemented with 10% FBS, 2 mM Glutamax,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent