Compile Data Set for Download or QSAR
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Found 2 Enz. Inhib. hit(s) with Target = 'Nuclear receptor subfamily 1 group I member 2' and Ligand = 'BDBM50609818'
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))TBA
LigandPNGBDBM50609818(CHEMBL5277255)
Affinity DataIC50:  4nMAssay Description:Inhibition of BODIPY FL vindoline binding to recombinant human GST-tagged PXR LBD (111 to 434 residues) expressed in baculovirus infected insect cell...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))TBA
LigandPNGBDBM50609818(CHEMBL5277255)
Affinity DataIC50:  9nMAssay Description:Antagonist activity at human PXR in human HepG2 cells co-expressing luciferase gene under control of CYP3A4 promoter assessed as inhibition in rifamp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed