Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'P2Y purinoceptor 1' and Ligand = 'BDBM50045610'
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50045610(CHEMBL3314290 | US9540323, 74 | US9540323, example...)
Affinity DataKi:  20nM ΔG°:  -43.9kJ/molepH: 7.4 T: 2°CAssay Description:A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50045610(CHEMBL3314290 | US9540323, 74 | US9540323, example...)
Affinity DataIC50:  0.0900nMAssay Description:Antagonist activity at P2Y1 receptor in washed human platelets assessed as 1 uM 2-methylthio-ADP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50045610(CHEMBL3314290 | US9540323, 74 | US9540323, example...)
Affinity DataIC50:  3.10E+3nMAssay Description:Antagonist activity at P2Y1 receptor in platelet-enriched human plasma assessed as 10 uM ADP-induced platelet aggregation preincubated for 1 min foll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed