Affinity DataKi: 13nM ΔG°: -45.0kJ/molepH: 7.4 T: 2°CAssay Description:A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we...More data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:Antagonist activity at P2Y1 receptor in washed human platelets assessed as 1 uM 2-methylthio-ADP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Antagonist activity at P2Y1 receptor in platelet-enriched human plasma assessed as 10 uM ADP-induced platelet aggregation preincubated for 1 min foll...More data for this Ligand-Target Pair