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Report error Found 6 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM368657'
LigandPNGBDBM368657(US10227350, Compound 105 | US10227350, Compound 10...)
Affinity DataIC50:  42nMAssay Description:Inhibition of human p110delta catalytic subunit/p85alpha using PIP2 as substrate after 30 mins in presence of ATP at 2xKm concentration by TR-FRET as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM368657(US10227350, Compound 105 | US10227350, Compound 10...)
Affinity DataIC50:  42nMAssay Description:Inhibition of full length human p110delta/p85alpha using PIP2 as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM368657(US10227350, Compound 105 | US10227350, Compound 10...)
Affinity DataIC50:  43nMAssay Description:Inhibition of full length human p110delta/p85alpha using PIP2 as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM368657(US10227350, Compound 105 | US10227350, Compound 10...)
Affinity DataIC50:  43nMAssay Description:Inhibition of human p110delta catalytic subunit/p85alpha using PIP2 as substrate after 30 mins in presence of ATP at 2xKm concentration by TR-FRET as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM368657(US10227350, Compound 105 | US10227350, Compound 10...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of full length human p110delta/p85alpha using PIP2 as substrate after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM368657(US10227350, Compound 105 | US10227350, Compound 10...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human p110delta catalytic subunit/p85alpha using PIP2 as substrate after 30 mins in presence of ATP at 2xKm concentration by TR-FRET as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB