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Report error Found 3 Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase 1' and Ligand = 'BDBM50288530'
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50288530(CHEMBL4098253)
Affinity DataIC50:  1.70nMAssay Description:Binding affinity to PARP1 in human OVCAR8 cells assessed as reduction in [125I]-KX1 binding by gamma counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50288530(CHEMBL4098253)
Affinity DataIC50:  2.80nMAssay Description:Displacement of [125I]KX1 from PARP1 in human OVCAR-8 cells incubated for 1 hr by wizard gamma counter analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50288530(CHEMBL4098253)
Affinity DataIC50:  5nMAssay Description:Inhibition of PARP-1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed