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Found 4 Enz. Inhib. hit(s) with Target = 'Potassium voltage-gated channel subfamily H member 2' and Ligand = 'BDBM223395'
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM223395(US9315520, 1 | US9315520, Comparator 1 | US9315520...)
Affinity DataIC50:  9.90E+3nMT: 2°CAssay Description:All testing was carried out in CHO cells transfected with the hERG gene purchased from Millipore (PrecisION hERG-CHO Recombinant Cell Line CYL3038). ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM223395(US9315520, 1 | US9315520, Comparator 1 | US9315520...)
Affinity DataIC50:  9.90E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells at holding potential of -80 mV by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM223395(US9315520, 1 | US9315520, Comparator 1 | US9315520...)
Affinity DataIC50:  9.90E+3nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells for 5 mins at -80 mV holding potential by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM223395(US9315520, 1 | US9315520, Comparator 1 | US9315520...)
Affinity DataIC50:  2.36E+4nMT: 2°CAssay Description:All testing was carried out in CHO cells transfected with the hERG gene purchased from Millipore (PrecisION hERG-CHO Recombinant Cell Line CYL3038). ...More data for this Ligand-Target Pair
In DepthDetails US Patent