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Report error Found 3 Enz. Inhib. hit(s) with Target = 'Prolyl endopeptidase' and Ligand = 'BDBM50434169'
TargetProlyl endopeptidase(Human)
Universiteit Antwerp

US Patent
LigandPNGBDBM50434169(CHEMBL2385300 | US9346814, Cmpd No 22 Example 26)
Affinity DataIC50: >5.00E+4nMpH: 8.3 T: 37°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetProlyl endopeptidase(Human)
Universiteit Antwerp

US Patent
LigandPNGBDBM50434169(CHEMBL2385300 | US9346814, Cmpd No 22 Example 26)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant PREP expressed in Escherichia coli using Z-Gly-Pro-p-nitroanilide as substrate incubated for 15 mins prior to substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Human)
Universiteit Antwerp

US Patent
LigandPNGBDBM50434169(CHEMBL2385300 | US9346814, Cmpd No 22 Example 26)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant human PREP purified from Escherichia coli using Z-Gly-Pro-p-nitroanilide as substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed