Affinity DataKi: 4.30nMAssay Description:Inhibition of [3H]PGD-2 binding to human chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2)More data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Binding affinity to human recombinant CRTH2 receptor by cell based radioligand equilibrium competition assayMore data for this Ligand-Target Pair
Affinity DataKi: 73nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 137nMAssay Description:Binding affinity to human recombinant CRTH2 receptor by cell based radioligand equilibrium competition assayMore data for this Ligand-Target Pair
Affinity DataKi: 290nMAssay Description:Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 290nMAssay Description:Inhibitory activity of the compound for PGD2-mediated receptor activation in a fluorescence assay that measures changes in intracellular calciumMore data for this Ligand-Target Pair
Affinity DataKi: 340nMAssay Description:Inhibitory concentration of the compound for PGD2-mediated receptor activation in a fluorescence assay that measures changes in intracellular calciumMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Antagonist activity against CRTh2 receptor in human eosinophils assessed as cell shape changeMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of beta-arrestin translocation at human chemoattractant receptor-homologous molecule expressed on TH2 cells in BRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of PGD2-induced inositol phosphate formation at human chemoattractant receptor-homologous molecule expressed on TH2 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 77nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 195nMAssay Description:Antagonist activity against CRTh2 receptor in human whole blood assessed as eosinophil shape changeMore data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Antagonist activity against human CRTh2 receptor expressed in CHO cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 311nMAssay Description:Displacement of [3H]PGD2 from human prostaglandin D2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 461nMAssay Description:Antagonist activity against human CRTh2 receptor expressed in CHO cells assessed as inhibition of PGD2-mediated Ca2+ fluxMore data for this Ligand-Target Pair
Affinity DataIC50: 754nMAssay Description:Displacement of [3H]PGD2 from human prostaglandin D2 receptor in presence of human serum albuminMore data for this Ligand-Target Pair