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Found 20 Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 1/2' and Ligand = 'BDBM17638'
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  2.90nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1/2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  10nMAssay Description:In vitro inhibitory activity against cyclooxygenase of human platelets was determinedMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  100nMAssay Description:Invitro inhibition of polymorphonuclear leukocyte derived human 5-lipoxygenaseMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1/2(Ovis aries (Sheep))
TBA

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  150nMAssay Description:Inhibition of ram seminal vesicle CyclooxygenaseMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity against Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibition of prostaglandin synthesis was tested in ratMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1/2(Ovis aries (Sheep))
TBA

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  300nMAssay Description:Inhibition of Prostaglandin G/H synthase of ram seminal vesicle microsomesMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1/2(Bos taurus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  430nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  500nMAssay Description:Tested for inhibition of cyclooxygenase (ARBC) in calcium-stimulated rat basophilic leukemia cells(RBL-1)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  500nMAssay Description:Inhibition of Prostaglandin G/H synthase in intact RBL-1 cell lineMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  500nMAssay Description:Concentration of the compound required to inhibit dog plasma renin by 50% using radio-immunoassay was determinedMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1/2(Bos taurus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of prostaglandin G/H synthase obtained from bovine seminal vesicles.More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1/2(Bos taurus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  1.00E+3nMAssay Description:Tested for Prostaglandin synthetase inhibition in Bovine seminal vesicle microsomes using Beckman liquid scintillation counter at 10 e-5 MMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1/2(Bos taurus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  1.10E+3nMAssay Description:Antiparasitic activity of the compound against thiamine transporter of Eimeria tenellaMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1/2(Bos taurus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of H-Ras-mediated farnesylation expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1/2(RAT)
Shionogi

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of prostaglandin synthetase in rat renal medullaMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1/2(Bos taurus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  1.80E+3nMAssay Description:Tested for its inhibitory activity against PGS (prostaglandin synthetase).More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1/2(Bos taurus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  1.80E+3nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase in BSV cell line.More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1/2(Ovis aries (Sheep))
TBA

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  1.72E+4nMAssay Description:Inhibition of ovine seminal vesicle prostaglandin synthetaseMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1/2(Bos taurus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  6.31E+8nMAssay Description:Ability to inhibit Prostaglandin G/H synthase was evaluated in vitro using bovine seminal vesicle preparations.More data for this Ligand-Target Pair