Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 2' and Ligand = 'BDBM50131593'
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Domp&Egrove

Curated by ChEMBL
LigandPNGBDBM50131593(4-[4-Chloro-5-(3-fluoro-4-methoxy-phenyl)-imidazol...)
Affinity DataIC50:  5nMAssay Description:In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Domp&Egrove

Curated by ChEMBL
LigandPNGBDBM50131593(4-[4-Chloro-5-(3-fluoro-4-methoxy-phenyl)-imidazol...)
Affinity DataIC50:  5nMAssay Description:Inhibition of COX-2 in human 143982 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Domp&Egrove

Curated by ChEMBL
LigandPNGBDBM50131593(4-[4-Chloro-5-(3-fluoro-4-methoxy-phenyl)-imidazol...)
Affinity DataIC50:  66nMAssay Description:In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Domp&Egrove

Curated by ChEMBL
LigandPNGBDBM50131593(4-[4-Chloro-5-(3-fluoro-4-methoxy-phenyl)-imidazol...)
Affinity DataIC50:  100nMAssay Description:Activity of COX2 in human heparinized blood assessed as inhibition of LPS-induced PGE2 production after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed