Found 5 Enz. Inhib. hit(s) with Target = 'Proteasome subunit beta type-2' and Ligand = 'BDBM50277889'
TargetProteasome subunit beta type-2(Homo sapiens (Human))
New Mexico Institute of Mining and Technology
Curated by ChEMBL
New Mexico Institute of Mining and Technology
Curated by ChEMBL
Affinity DataIC50: 203nMAssay Description:Inhibition of 20S proteasome beta2 subunit in human Jurkat cell lysate using Suc-RLR-AMC as substrate pretreated for 30 mins followed by substrate ad...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
New Mexico Institute of Mining and Technology
Curated by ChEMBL
New Mexico Institute of Mining and Technology
Curated by ChEMBL
Affinity DataIC50: 825nMAssay Description:Inhibition of human trypsin-like activity of 20S constitutive proteasome using Z-VLR-AMC as substrate preincubated for 15 mins followed by substrate ...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
New Mexico Institute of Mining and Technology
Curated by ChEMBL
New Mexico Institute of Mining and Technology
Curated by ChEMBL
Affinity DataIC50: 1.81E+3nMAssay Description:Inhibition of human 20s proteasome subunit beta2 caspase-like activity using Z-LLE-AMC as substrate preincubated for 15 mins followed by substrate ad...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
New Mexico Institute of Mining and Technology
Curated by ChEMBL
New Mexico Institute of Mining and Technology
Curated by ChEMBL
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of 20S proteasome beta 2c (unknown origin) after 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
New Mexico Institute of Mining and Technology
Curated by ChEMBL
New Mexico Institute of Mining and Technology
Curated by ChEMBL
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of human platelet Thromboxane synthetaseMore data for this Ligand-Target Pair