BindingDB PrimarySearch

Report error Found 2 Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50126339'

Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
University of Minnesota

Curated by ChEMBL

BDBM50126339(4-[(3-CYANO-BENZYL)-(3-METHYL-3H-IMIDAZOL-4-YLMETH...)

IC50: 0.390nMAssay Description:Inhibition of human recombinant FTase using [3H]farnesyldiphosphateMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL MMDB PC cid PC sid PDB Similars

Details Article PubMed MMDB
PDB

3D Structure (crystal)

Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bovine)
Abbott Laboratories

Curated by ChEMBL

BDBM50126339(4-[(3-CYANO-BENZYL)-(3-METHYL-3H-IMIDAZOL-4-YLMETH...)

IC50: 0.390nMAssay Description:In vitro inhibitory activity of the compound against farnesyltransferase (FTase)More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL MMDB PC cid PC sid PDB Similars

Details Article PubMed MMDB
PDB

3D Structure (crystal)