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Found 2 Enz. Inhib. hit(s) with Target = 'Protein-serine O-palmitoleoyltransferase porcupine' and Ligand = 'BDBM374846'
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM374846(US10251893, Cpd 50)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM374846(US10251893, Cpd 50)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed