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Report error Found 7 Enz. Inhib. hit(s) with Target = 'Purine nucleoside phosphorylase' and Ligand = 'BDBM50042800'
TargetPurine nucleoside phosphorylase(Bovine)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50042800(2-Amino-7-cyclohexylmethyl-3,5-dihydro-pyrrolo[3,2...)
Affinity DataKi:  6.40nMAssay Description:Inhibitory activity against calf spleen purine nucleoside phosphorylase (PNP) using 2-amino-6-mercapto-7-methyl purine ribonucleoside (MESG) as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Bovine)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50042800(2-Amino-7-cyclohexylmethyl-3,5-dihydro-pyrrolo[3,2...)
Affinity DataKi:  13.2nMAssay Description:Inhibitory activity against calf spleen purine nucleoside phosphorylase (PNP) using inosine as substrate at a concentration of 10 uM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Bovine)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50042800(2-Amino-7-cyclohexylmethyl-3,5-dihydro-pyrrolo[3,2...)
Affinity DataIC50:  21nMAssay Description:Inhibitory activity against calf spleen purine nucleoside phosphorylase (PNP) using inosine as substrate at a concentration of 10 uM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Bovine)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50042800(2-Amino-7-cyclohexylmethyl-3,5-dihydro-pyrrolo[3,2...)
Affinity DataIC50:  47nMAssay Description:In vitro inhibition of purine nucleoside phosphorylase from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50042800(2-Amino-7-cyclohexylmethyl-3,5-dihydro-pyrrolo[3,2...)
Affinity DataIC50:  47nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 1 mM PO4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50042800(2-Amino-7-cyclohexylmethyl-3,5-dihydro-pyrrolo[3,2...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 50 mM PO4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Bovine)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50042800(2-Amino-7-cyclohexylmethyl-3,5-dihydro-pyrrolo[3,2...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of purine nucleoside phosphorylase from calf spleen in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed