Report error Found 3 Enz. Inhib. hit(s) with Target = 'RAF proto-oncogene serine/threonine-protein kinase [Y340E,Y341E]' and Ligand = 'BDBM202682'
Affinity DataIC50: 0.100nMpH: 7.5 T: 25°CAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMpH: 7.5 T: 25°CAssay Description:Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMpH: 7.5 T: 25°CAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair