Found 12 Enz. Inhib. hit(s) with Target = 'Receptor-type tyrosine-protein kinase FLT3' and Ligand = 'BDBM50250180'
Affinity DataIC50: 9nMAssay Description:Inhibition of FLT3-ITD mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 91nMAssay Description:Inhibition of wild type FLT3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 91nMAssay Description:Inhibition of FLT3 in human MV4-11 cells assessed as inhibition of STAT5 phosphorylation at Tyr694 site after 4 hrs by immunoblotting analysisMore data for this Ligand-Target Pair
Affinity DataEC50: <10nMAssay Description:Inhibition of FLT3 in human MOLM4 cells assessed as inhibition of ERK phosphorylation at Thr202/Tyr204 site after 4 hrs by immunoblotting analysisMore data for this Ligand-Target Pair
Affinity DataEC50: <10nMAssay Description:Inhibition of FLT3 in human MOLM14 cells assessed as inhibition of Akt phosphorylation at Thr308/Ser473 site after 4 hrs by immunoblotting analysisMore data for this Ligand-Target Pair
Affinity DataEC50: <10nMAssay Description:Inhibition of full length recombinant human His-tagged CDK7/Cyclin H/MNAT1 expressed in Baculovirus expression system by Z'Lyte assayMore data for this Ligand-Target Pair
Affinity DataEC50: <10nMAssay Description:Inhibition of full length recombinant human His-tagged CDK8/Cyclin C expressed in Baculovirus expression system by Z'Lyte assayMore data for this Ligand-Target Pair
Affinity DataEC50: <10nMAssay Description:Inhibition of FLT3 in human MOLM13 cells assessed as inhibition of Akt phosphorylation at Thr308/Ser473 site after 4 hrs by immunoblotting analysisMore data for this Ligand-Target Pair
Affinity DataEC50: <10nMAssay Description:Inhibition of FLT3 in human MOLM13 cells assessed as inhibition of ERK phosphorylation at Thr202/Tyr204 site after 4 hrs by immunoblotting analysisMore data for this Ligand-Target Pair
Affinity DataEC50: <10nMAssay Description:Inhibition of FLT3 in human MOLM14 cells assessed as inhibition of STAT5 phosphorylation at Tyr694 site after 4 hrs by immunoblotting analysisMore data for this Ligand-Target Pair
Affinity DataEC50: <10nMAssay Description:Inhibition of FLT3 in human MV4-11 cells assessed as inhibition of ERK phosphorylation at Thr202/Tyr204 site after 4 hrs by immunoblotting analysisMore data for this Ligand-Target Pair
Affinity DataEC50: <10nMAssay Description:Inhibition of FLT3 in human MV4-11 cells assessed as inhibition of Akt phosphorylation at Thr308/Ser473 site after 4 hrs by immunoblotting analysisMore data for this Ligand-Target Pair