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Report error Found 2 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM50328597'
TargetSerine/threonine-protein kinase mTOR(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50328597(CHEMBL1256454 | N-(4-(2-oxo-1-(4-(piperazin-1-yl)-...)
Affinity DataIC50:  46nMAssay Description:Inhibition of human mTOR complex 1 after 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Mouse)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50328597(CHEMBL1256454 | N-(4-(2-oxo-1-(4-(piperazin-1-yl)-...)
Affinity DataIC50: >300nMAssay Description:Inhibition of mTOR in p53-deficient MEF assessed as phosphorylation of S6K1 at Thr389 by immunoblottingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed