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Found 3 Enz. Inhib. hit(s) with Target = 'Sodium/glucose cotransporter 2' and Ligand = 'BDBM50340012'
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50340012(6,8-dichloro-4-((5-(4-chlorophenethyl)-4-propyl-4H...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50340012(6,8-dichloro-4-((5-(4-chlorophenethyl)-4-propyl-4H...)
Affinity DataIC50:  16nMAssay Description:Displacement of [3H]dapagliflozin from human SGLT2 expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50340012(6,8-dichloro-4-((5-(4-chlorophenethyl)-4-propyl-4H...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed