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Found 3 Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 2 subunit alpha' and Ligand = 'BDBM50233224'
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Tohoku University

Curated by ChEMBL
LigandPNGBDBM50233224(CHEMBL4070670)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at human Nav1.2 expressed in HEK293T cells assessed as inhibition of VTD-induced tail current by whole cell patch clamp method re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Tohoku University

Curated by ChEMBL
LigandPNGBDBM50233224(CHEMBL4070670)
Affinity DataIC50:  2.10nMAssay Description:Antagonist activity at human Nav1.2 expressed in HEK293T cells assessed as inhibition of VTD-induced sustained current by whole cell patch clamp meth...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Tohoku University

Curated by ChEMBL
LigandPNGBDBM50233224(CHEMBL4070670)
Affinity DataEC50:  120nMAssay Description:Inhibition of Nav1.2 (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed