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Found 4 Enz. Inhib. hit(s) with Target = 'Sodium-dependent noradrenaline transporter' and Ligand = 'BDBM50297365'
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50297365((1S,2R)-1-(1H-indol-1-yl)-3-(methylamino)-1-phenyl...)
Affinity DataIC50:  23nMAssay Description:Displacement of [3H]Nisoxetine from human recombinant NET expressed in MDCK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50297365((1S,2R)-1-(1H-indol-1-yl)-3-(methylamino)-1-phenyl...)
Affinity DataIC50:  28nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50297365((1S,2R)-1-(1H-indol-1-yl)-3-(methylamino)-1-phenyl...)
Affinity DataIC50:  28nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50297365((1S,2R)-1-(1H-indol-1-yl)-3-(methylamino)-1-phenyl...)
Affinity DataIC50:  137nMAssay Description:Inhibition of norepinephrine reuptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed