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Found 2 Enz. Inhib. hit(s) with Target = 'Sodium-dependent serotonin transporter' and Ligand = 'BDBM433681'
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM433681(US10562878, Compound 256)
Affinity DataIC50:  69nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM433681(US10562878, Compound 256)
Affinity DataIC50:  280nMAssay Description:Quantification of 5-HT uptake was performed using synaptosomes isolated in a 0.32M sucrose buffer from a male Wistar rat cortex. The uptake of radiol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent