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Found 2 Enz. Inhib. hit(s) with Target = 'Sphingomyelin phosphodiesterase 3' and Ligand = 'BDBM50540368'
TargetSphingomyelin phosphodiesterase 3(Homo sapiens)
Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50540368(CHEMBL4649186 | US11427590, Entry 39b-PROV)
Affinity DataIC50:  800nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingomyelin phosphodiesterase 3(Homo sapiens)
Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50540368(CHEMBL4649186 | US11427590, Entry 39b-PROV)
Affinity DataIC50: <1.00E+3nMAssay Description:The fluorescence based assay to monitor the activity of human nSMase2 in the presence or absence of potential inhibitors has been described recently....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent