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Found 2 Enz. Inhib. hit(s) with Target = 'Steroid 17-alpha-hydroxylase/17,20 lyase' and Ligand = 'BDBM8892'
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Universitat Des Saarlandes

US Patent
LigandPNGBDBM8892(3-(1-Methyl-3,4-dihydronaphthalen-2-yl)-pyridine |...)
Affinity DataIC50:  1.09E+3nMpH: 7.4 T: 2°CAssay Description:A solution of 6.25 nmol of progesterone (in 5 μl of MeOH) was dissolved in 140 μl of phosphate buffer (0.05 M; pH 7.4; 1 mM MgCl2; 0.1 mM EDTA ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Universitat Des Saarlandes

US Patent
LigandPNGBDBM8892(3-(1-Methyl-3,4-dihydronaphthalen-2-yl)-pyridine |...)
Affinity DataIC50:  1.09E+3nMAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed