Report error Found 6 Enz. Inhib. hit(s) with Target = 'Thymidylate synthase' and Ligand = 'BDBM18772'
Affinity DataKi: 800nM ΔG°: -34.2kJ/molepH: 7.0 T: 20°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
Affinity DataKi: 4.10E+3nM ΔG°: -30.2kJ/molepH: 7.0 T: 20°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
Affinity DataKi: 4.10E+3nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
Affinity DataKi: 2.80E+4nM ΔG°: -25.6kJ/molepH: 7.0 T: 20°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
Affinity DataKi: >2.45E+5nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
Affinity DataKi: >2.45E+5nM ΔG°: >-20.3kJ/molepH: 7.0 T: 20°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair